How many refills can be prescribed for a Schedule II substance like morphine?

Schedule II substances, such as morphine, are highly regulated due to their potential for abuse and dependence. Under federal law in the United States, a prescription for a Schedule II controlled substance cannot include any refills. This means that once the prescription is filled, a new prescription must be written for any further supply. This regulation is in place to ensure careful monitoring of the usage of these medications and to reduce the risk of addiction and misuse. Therefore, the correct response reflects the strict guidelines governing the prescription of Schedule II drugs.