Which class of antibiotics is commonly used to treat atypical pneumonia?

Atypical pneumonia is often caused by pathogens like Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella pneumophila, which do not respond well to standard beta-lactam antibiotics such as penicillins. Macrolides, specifically azithromycin and clarithromycin, are effective against these atypical pathogens due to their ability to inhibit protein synthesis in bacteria.

Macrolides are typically preferred for treating atypical pneumonia because they have good tissue penetration and can effectively target the intracellular organisms responsible for this type of pneumonia. Additionally, macrolides have a favorable side effect profile and can also be used in patients who may be allergic to penicillins.

While quinolones and tetracyclines can also be used for the treatment of atypical pneumonia, macrolides are more commonly the first-line choice in many clinical scenarios due to their well-established efficacy and safety profile.