Which class of antibiotics is used to treat Pseudomonas infections?

Fluoroquinolones are a class of antibiotics that are particularly effective against Pseudomonas aeruginosa, a common opportunistic pathogen known for its resistance to multiple antibiotics. This effectiveness is largely due to the broad spectrum of activity that fluoroquinolones provide, including treatment for both Gram-negative and some Gram-positive bacteria.

Fluoroquinolones, such as ciprofloxacin and levofloxacin, target the bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication and leading to cell death. Their pharmacokinetics allow good tissue penetration, making them suitable for infections caused by Pseudomonas, especially in various clinical settings like urinary tract infections, respiratory infections, or cases of bacterial keratitis.

Other antibiotic classes mentioned, such as macrolides, cephalosporins, and tetracyclines, generally do not have reliable activity against Pseudomonas. Macrolides primarily target atypical pathogens and are not considered effective against this particular bacterium. Although some cephalosporins (like third-generation and advanced-generation ones) have some efficacy against Pseudomonas, fluoroquinolones are often preferred due to their demonstrated broader and more reliable coverage. Tetracy